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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Bexarotene/5819/50/50 mg
产品编号:5819/50
市  场 价:¥6300.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$315.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Bexarotene/5819/50/50 mg
商品介绍
Description:PotentandselectiveRXRagoNIST
AlternativeNames:LGD1069
ChemicalName:4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoicacid
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveRXRagonist(EC50valuesare24,25and33nMforRXRβ,RXRγandRXRα,respectively).Exhibits>300-foldselectivityforRXRoverRARreceptors.Inhibitstumorcellinvasionandmigrationinvitro,andinhibitsmetastasisandangiogenesisinmousemodels.AlsopromotesbrownADIpogenicdifferentiationandinducesbrownadipogenicreprogrammingfrommyoblasts.

TechnicalData

M.Wt348.48
FormulaC24H28O2
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber153559-49-0
PubChemID82146
InChIKeyNAVMQTYZDKMPEU-UHFFFAOYSA-N
SmilesCC(CCC(C)2C)(C)C1=C2C=C(C)C(C(C3=CC=C(C(O)=O)C=C3)=C)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO34.85100
ethanol6.9720mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight348.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.87mL14.35mL28.7mL
5mM0.57mL2.87mL5.74mL
10mM0.29mL1.43mL2.87mL
50mM0.06mL0.29mL0.57mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet