PotentinhibitorofBax-mediatedmitochondrialcytochromecrelease(IC50=0.52μM).SuggestedtoinhibitBaxchannelformation/activity.
BaxchannelblockerisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 540.12 |
Formula | C19H21Br2N3O.2HCl |
Storage | DesiccateatRT |
Purity | ≥98%(HPLC) |
CASNumber | 329349-20-4 |
PubChemID | 2729026 |
InChIKey | HWFKCAFKXZFOQT-UHFFFAOYSA-N |
Smiles | Cl.Cl.OC(CN1C2=C(C=C(Br)C=C2)C2=C1C=CC(Br)=C2)CN1CCNCC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 46.72 | 100 | |
water | 2.34 | 5 |
Thefollowingdataisbasedontheproductmolecularweight540.12.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 1.85mL | 9.26mL | 18.51mL |
5mM | 0.37mL | 1.85mL | 3.7mL |
10mM | 0.19mL | 0.93mL | 1.85mL |
50mM | 0.04mL | 0.19mL | 0.37mL |