Macrophagemigrationinhibitoryfactor(MIF)binder(Kd=68.6nM).Activatesantioxidantresponseelement(ARE)-mediatedgeneexpression.Suppressesoxidativestress-inducedcardiomyocyteapoptosisinvitro.Cardioprotective.
M.Wt | 240.28 |
Formula | C13H8N2OS |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 99420-15-2 |
PubChemID | 9837640 |
InChIKey | GBAKVEWPYUIGHN-UHFFFAOYSA-N |
Smiles | O=C2C1=CC=CC=C1SC(C3=NC=CC=C3)=N2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 4.81 | 20mMwithgentlewarming |
Thefollowingdataisbasedontheproductmolecularweight240.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 4.16mL | 20.81mL | 41.62mL |
5mM | 0.83mL | 4.16mL | 8.32mL |
10mM | 0.42mL | 2.08mL | 4.16mL |
50mM | 0.08mL | 0.42mL | 0.83mL |