Inhibitorofleukemiastemcell(LSC)activity(EC50=200nM).Exhibits>100-foldselectivityforLSCsovernormalhematopoieticstemcells.
| M.Wt | 496.66 |
| Formula | C28H36N2O4S |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 329059-55-4 |
| PubChemID | 981129 |
| InChIKey | UHXFWAHRAMUDLJ-UHFFFAOYSA-N |
| Smiles | O=C(C1C(C)(C)C1(C)C)NC(C=C2)=CC=C2S(C3=CC=C(NC(C4C(C)(C)C4(C)C)=O)C=C3)(=O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 49.67 | 100 | |
| ethanol | 9.93 | 20 |
Thefollowingdataisbasedontheproductmolecularweight496.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.01mL | 10.07mL | 20.13mL |
| 5mM | 0.4mL | 2.01mL | 4.03mL |
| 10mM | 0.2mL | 1.01mL | 2.01mL |
| 50mM | 0.04mL | 0.2mL | 0.4mL |



