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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/BPIPP/3635/10/10 mg
产品编号:3635/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/BPIPP/3635/10/10 mg
商品介绍
Description:Non-competitiveGCinhibitor.AlsoACinhibitor
ChemicalName:5-(3-Bromophenyl)-5,11-dihydro-1,3-dimethyl-1H-indeno[2',1':5,6]pyrido[2,3-d]pyrimidine-2,4,6(3H)-trione
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Non-competitiveguanylylcyclase(GC)andadenylylcyclase(AC)inhibitor.DownregulatescAMPandcGMPsynthesis,andsuppressescGMPaccumulationinavarietyofcelllines(IC50=3.4-11.2μM).InhibitsGC-stimulatedCl-transportinvitroandsuppressestoxin-inducedintestinalfluidaccumulationinvivo.

TechnicalData

M.Wt450.28
FormulaC22H16BrN3O3
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber325746-94-9
PubChemID4410990
InChIKeyQSZKQDDYOLAPII-UHFFFAOYSA-N
SmilesO=C(C5=C4C=CC=C5)C2=C4NC(N1C)=C(C2C3=CC(Br)=CC=C3)C(N(C)C1=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO0.92

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight450.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.22mL11.1mL22.21mL
5mM0.44mL2.22mL4.44mL
10mM0.22mL1.11mL2.22mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet