Highlypotentandselectiveandrogenreceptor(AR)agonist(EC50=0.44nM).ExhibitsselectivityforARsoverestrogen,glucocorticoidandmineralocorticoidreceptorsandnosignificantbindingtosteroidhormonebindingglobulinoraromatase.AlsoexhibitsselectivityformuscleoverprostateARs.Activeinvivoandorallybioavailable.
M.Wt | 305.72 |
Formula | C14H12ClN3O3 |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 627530-84-1 |
PubChemID | 49823417 |
InChIKey | KEJORAMIZFOODM-UHFFFAOYSA-N |
Smiles | [H][C@@]12[C@H](O)CCN1C(=O)N(C2=O)C1=CC=C(C#N)C(Cl)=C1C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 30.57 | 100 |
Thefollowingdataisbasedontheproductmolecularweight305.72.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.27mL | 16.35mL | 32.71mL |
5mM | 0.65mL | 3.27mL | 6.54mL |
10mM | 0.33mL | 1.64mL | 3.27mL |
50mM | 0.07mL | 0.33mL | 0.65mL |