BiP(Hsp70-5)ERchaperoneinducer;inducesBiPexpressioninvitroandinvivo.ProtectsagainstER-stressinducedcelldeathinneuronalandretinalcelllines.Alsoprotectsagainstischaemia-inducedhippocampalcelldeathinvivo.
M.Wt | 209.22 |
Formula | C9H7NO3S |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 101714-41-4 |
PubChemID | 16656807 |
InChIKey | SVFLBLCWKKQKDW-UHFFFAOYSA-N |
Smiles | O=C(CSC#N)C1=CC=C(O)C(O)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 20.92 | 100 | |
ethanol | 20.92 | 100 |
Thefollowingdataisbasedontheproductmolecularweight209.22.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 4.78mL | 23.9mL | 47.8mL |
5mM | 0.96mL | 4.78mL | 9.56mL |
10mM | 0.48mL | 2.39mL | 4.78mL |
50mM | 0.1mL | 0.48mL | 0.96mL |