PotentandselectiveGABABreceptorpositiveallostericmodulatorthatincreasesthepotencyandefficacyofGABA(>15-foldand>149%respectively).Exhibitsanxiolyticactivityinvivoandisorallyactive.
racBHFFisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 330.34 |
Formula | C17H21F3O3 |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 123557-91-5 |
PubChemID | 4332683 |
InChIKey | RVNOANDLZIIFHB-UHFFFAOYSA-N |
Smiles | CC(C)(C)C1=C2C(C(O)(C(F)(F)F)C(O2)=O)=CC(C(C)(C)C)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 33.03 | 100 | |
ethanol | 33.03 | 100 |
Thefollowingdataisbasedontheproductmolecularweight330.34.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.03mL | 15.14mL | 30.27mL |
5mM | 0.61mL | 3.03mL | 6.05mL |
10mM | 0.3mL | 1.51mL | 3.03mL |
50mM | 0.06mL | 0.3mL | 0.61mL |