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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/BGC 20-1531 hydrochloride/5327/10/10 mg
产品编号:5327/10
市  场 价:¥5980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$299.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/BGC 20-1531 hydrochloride/5327/10/10 mg
商品介绍
Description:HighaffinityandselectiveEP4antagoNIST
AlternativeNames:PGN1531
ChemicalName:4-[[4-(5-Methoxy-2-pyridinyl)phenoxy]methyl]-5-methyl-N-[(2-methylphenyl)sulfonyl]-2-furancarboxamidehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighaffinityandselectiveEP4antagonist(Ki=3nM).Exhibits>2500-foldselectivityforEP4overEP2andEP3.Alsoselectiveoverarangeofotherprostanoidreceptors,ionchannels,transportersandenzymes.InhibitsPGE2-inducedvasodilationofmiddlecerebralandmeningealarteriesinvitro,andcarotidbloodflowinvivo.Orallybioavailable.

TechnicalData

M.Wt529
FormulaC26H24N2O6S.HCl
StorageDesiccateatRT
Purity≥98%(HPLC)
PubChemID121513858
InChIKeyZSHYZCXOFPPBMH-UHFFFAOYSA-N
SmilesCC(OC(C(NS(C4=CC=CC=C4C)(=O)=O)=O)=C3)=C3COC(C=C2)=CC=C2C1=NC=C(OC)C=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO49.25100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight529.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.89mL9.45mL18.9mL
5mM0.38mL1.89mL3.78mL
10mM0.19mL0.95mL1.89mL
50mM0.04mL0.19mL0.38mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet