HistamineH3receptorinverseagonist(EC50=1.5nM)andantagonist(Ki=0.16nM).Exhibitsnootropiceffectsincognitivedisorders;reduceslocomotorhyperactivityinducedbymethamphetamine.Brainpenetrant.
BF2649hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 332.31 |
Formula | C17H26ClNO.HCl |
Storage | DesiccateatRT |
Purity | ≥98%(HPLC) |
CASNumber | 903576-44-3 |
PubChemID | 11551689 |
InChIKey | XLFKECRRMPOAQS-UHFFFAOYSA-N |
Smiles | ClC1=CC=C(CCCOCCCN2CCCCC2)C=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 33.23 | 100 | |
ethanol | 33.23 | 100 | |
water | 33.23 | 100 |
Thefollowingdataisbasedontheproductmolecularweight332.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.01mL | 15.05mL | 30.09mL |
5mM | 0.6mL | 3.01mL | 6.02mL |
10mM | 0.3mL | 1.5mL | 3.01mL |
50mM | 0.06mL | 0.3mL | 0.6mL |