CysteinylleukotrienereceptorantagonistwithequalaffinityatbothCysLT1andCysLT2receptors(pKBvaluesare6.8and6.5respectively).CompetitiveantagonistofLTC4-andLTE4-inducedcontractionsoftheguineapigtrachea.
M.Wt | 472.64 |
Formula | C27H36O5S |
Storage | Storeat-80°C |
CASNumber | 154978-38-8 |
PubChemID | 5311015 |
InChIKey | PKJINWOACFYDQN-RBVMPENBSA-N |
Smiles | CCCCCC=C/C/C=CC=CC=C[C@@H](SC1=CC=C(C(O)=O)C=C1)[C@@H](O)CCCC(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solubility | Solubleinethanol(suppliedpre-dissolvedinEthanol,0.1mg/ml) |
Thefollowingdataisbasedontheproductmolecularweight472.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.12mL | 10.58mL | 21.16mL |
5mM | 0.42mL | 2.12mL | 4.23mL |
10mM | 0.21mL | 1.06mL | 2.12mL |
50mM | 0.04mL | 0.21mL | 0.42mL |