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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/BAY-u 3405/2732/10/10 mg
产品编号:2732/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/BAY-u 3405/2732/10/10 mg
商品介绍
Description:DualTP/DP2(CRTH2)receptorantagoNIST
AlternativeNames:Ramatroban
ChemicalName:(3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoicacid
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentdualantagonistofTP/DP2(CRTH2)prostanoidreceptors(Kivaluesare4.3,4.5and>10000nMforhDP2,hTPandhDP1receptorsrespectively).SuppressesPGD2-inducedmigrationofhumaneosinophils(IC50=170nM).

TechnicalData

M.Wt416.47
FormulaC21H21FN2O4S
StorageDesiccateat-20°C
Purity≥99%(HPLC)
CASNumber116649-85-5
PubChemID123879
InChIKeyLDXDSHIEDAPSSA-OAHLLOKOSA-N
SmilesFC(C=C4)=CC=C4S(N[C@@H](C3)CCC2=C3C1=CC=CC=C1N2CCC(O)=O)(=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO41.65100
ethanol41.65100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight416.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.4mL12.01mL24.01mL
5mM0.48mL2.4mL4.8mL
10mM0.24mL1.2mL2.4mL
50mM0.05mL0.24mL0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet