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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/BAY 60-6583/4472/10/10 mg
产品编号:4472/10
市  场 价:¥3700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$185.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/BAY 60-6583/4472/10/10 mg
商品介绍
Description:PotentA2BreceptoragoNIST;cardioprotective
ChemicalName:2-[[6-Amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentadenosineA2Breceptoragonist(EC50=2.83nMformurineA2Breceptor).DisplaysselectivityforA2BoverA1,A2AandA3receptors.DecreasesfMLP-inducedsuperoxideproductioninneutrophilsatlowconcentrations(1-10nM).Cardioprotective;attenuatesinfarctsizeinamousemodelofmyocardialischemia.

CompoundLibraries

BAY60-6583isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt379.44
FormulaC19H17N5O2S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber910487-58-0
PubChemID11717831
InChIKeyZTYHZMAZUWOXNC-UHFFFAOYSA-N
SmilesNC1=NC(SCC(N)=O)=C(C#N)C(C2=CC=C(OCC3CC3)C=C2)=C1C#N

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO37.94100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight379.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.64mL13.18mL26.35mL
5mM0.53mL2.64mL5.27mL
10mM0.26mL1.32mL2.64mL
50mM0.05mL0.26mL0.53mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet