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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/BAN ORL 24/3661/10/10 mg
产品编号:3661/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/BAN ORL 24/3661/10/10 mg
商品介绍
Description:PotentandselectiveNOPantagoNIST
ChemicalName:(2R)-1-(Phenylmethyl)-N-[3-(spiro[isobenzofuran-1(3H),4'-piperidin]-1-yl)propyl-2-pyrrolidinecarboxamide
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveNOPreceptorantagonist(IC50valuesare0.27,2500,6700and>10000nMforNOP,κ-,μ-andδ-receptorsrespectively).Inhibitsnociceptin-inducedstimulationof[35S]-GTPγSbindingandCa2+mobilizationinCHOcellsinvitroandantagonizesNOPagonist-inducedreductioninlocomotoractivityinvivo.Brainpenetrant.

CompoundLibraries

BANORL24isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt506.51
FormulaC27H35N3O2.2HCl
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber1401463-54-4
PubChemID56840444
InChIKeyNEEVITHVDIQNJY-KHZPMNTOSA-N
SmilesO=[C@@]([C@H]2CCCN2CC3=CC=CC=C3)NCCCN1CCC4(OCC5=C4C=CC=C5)CC1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO50.65100
water50.65100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight506.51.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.97mL9.87mL19.74mL
5mM0.39mL1.97mL3.95mL
10mM0.2mL0.99mL1.97mL
50mM0.04mL0.2mL0.39mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet