PromotesinclusionformationincellularmodelsofHuntington'sdiseaseandParkinson'sdisease.Preventsmutanthuntingtin-mediatedproteasomedysfunctionandreducesα-synuclein-mediatedtoxicity.
M.Wt | 396.83 |
Formula | C20H17ClN4O3 |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 115687-05-3 |
PubChemID | 3953303 |
InChIKey | KLNPVNZJCWIQSK-UHFFFAOYSA-N |
Smiles | O=C(C4=CC=C(Cl)C=C4)N(CC3)CCN3C1=C(C=CC=N2)C2=C([N+]([O-])=O)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 39.68 | 100 | |
ethanol | 3.97 | 10 |
Thefollowingdataisbasedontheproductmolecularweight396.83.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.52mL | 12.6mL | 25.2mL |
5mM | 0.5mL | 2.52mL | 5.04mL |
10mM | 0.25mL | 1.26mL | 2.52mL |
50mM | 0.05mL | 0.25mL | 0.5mL |