PromotesinclusionformationincellularmodelsofHuntington'sdiseaseandParkinson'sdisease.Preventsmutanthuntingtin-mediatedproteasomedysfunctionandreducesα-synuclein-mediatedtoxicity.
| M.Wt | 396.83 |
| Formula | C20H17ClN4O3 |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 115687-05-3 |
| PubChemID | 3953303 |
| InChIKey | KLNPVNZJCWIQSK-UHFFFAOYSA-N |
| Smiles | O=C(C4=CC=C(Cl)C=C4)N(CC3)CCN3C1=C(C=CC=N2)C2=C([N+]([O-])=O)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 39.68 | 100 | |
| ethanol | 3.97 | 10 |
Thefollowingdataisbasedontheproductmolecularweight396.83.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.52mL | 12.6mL | 25.2mL |
| 5mM | 0.5mL | 2.52mL | 5.04mL |
| 10mM | 0.25mL | 1.26mL | 2.52mL |
| 50mM | 0.05mL | 0.25mL | 0.5mL |



