Selectiveandpotentcalmodulin-dependentproteinkinaseII(CaMkinaseII)inhibitor(IC50=40nM).SelectiveoverPKC,PKAandCaMkinaseIV(IC50>10μM).
M.Wt | 1497.76 |
Formula | C64H116N22O19 |
Sequence | KKALRRQEAVDAL |
Storage | Desiccateat-20°C |
CASNumber | 167114-91-2 |
PubChemID | 25031982 |
InChIKey | USSJDGBHUQEJJG-HKDQSZHBSA-N |
Smiles | [H]N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solubility | Solubleto1mg/mlinwater |
Thefollowingdataisbasedontheproductmolecularweight1497.76.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 0.67mL | 3.34mL | 6.68mL |
5mM | 0.13mL | 0.67mL | 1.34mL |
10mM | 0.07mL | 0.33mL | 0.67mL |
50mM | 0.01mL | 0.07mL | 0.13mL |