Endogenouspeptideproducedbytheheart;involvedinbloodpressureregulation.Producesnatriuresis,diuresisandvasorelaxationinvivo.
M.Wt | 3080.46 |
Formula | C127H205N45O39S3 |
Sequence | SLRRSSCFGGRMDRIGAQSGLGCNSFRY (Modifications:Disulfidebridgebetween7-23) |
Storage | Desiccateat-20°C |
CASNumber | 91917-63-4 |
PubChemID | 16129708 |
InChIKey | NSQLIUXCMFBZME-MPVJKSABSA-N |
Smiles | [H]N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H]1CSSC[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)[C@H](CC2=CC=CC=C2)NC1=O)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solubility | Solubleto1mg/mlinwater |
Thefollowingdataisbasedontheproductmolecularweight3080.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 0.32mL | 1.62mL | 3.25mL |
5mM | 0.06mL | 0.32mL | 0.65mL |
10mM | 0.03mL | 0.16mL | 0.32mL |
50mM | 0.01mL | 0.03mL | 0.06mL |