JAK2inhibitor(IC50=397nM).AlsoinhibitsSTAT3andSTAT5phosphorylation.InhibitscellgrowthandinducesapoptosisincellsexpressingtheJAK2V617Fmutation.
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Thefollowingdataisbasedontheproductmolecularweight409.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.