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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Artemisinin/2668/50/50 mg
产品编号:2668/50
市  场 价:¥1500.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$75.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Artemisinin/2668/50/50 mg
商品介绍
Description:Antimalarial;inhibitsP-typeATPase(PfATP6)ofP.falciparum
AlternativeNames:Qinghaosu
ChemicalName:(3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Antimalarialagent;interactswithhemetoproducecarbon-centredfreerADIcals,causesproteinalkylationanddamagesparasitemicroorganellesandmembranes.AlsoselectivelyinhibitstheP-typeATPase(PfATP6)ofPlasmodiumfalciparum(Ki~150nM).Displaysantiangiogeniceffectsinmouseembryonicstemcell-derivedembryoidbodies.

CompoundLibraries

ArtemisininisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt282.33
FormulaC15H22O5
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber63968-64-9
PubChemID68827
InChIKeyBLUAFEHZUWYNDE-NNWCWBAJSA-N
SmilesO=C1O[C@]([H])(O[C@@](OO4)(C)CC3)[C@]24[C@](CC[C@@H](C)[C@]32[H])([H])[C@H]1C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO28.23100
ethanol21.1775

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight282.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.54mL17.71mL35.42mL
5mM0.71mL3.54mL7.08mL
10mM0.35mL1.77mL3.54mL
50mM0.07mL0.35mL0.71mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet