请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Arctigenin/1777/50/50 mg
产品编号:1777/50
市  场 价:¥7500.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$375.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Arctigenin/1777/50/50 mg
商品介绍
Description:PotentMEK1inhibitor.AlsoinhibitsIκBαphosphorylation
AlternativeNames:(-)-Arctigenin
ChemicalName:(3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Antioxidant,anti-inflammatory,antiproliferativeandantiviralagent.InhibitsLPS-inducediNOSexpressionviainhibitionofIκBαphosphorylationandp65nucleartranslocation(IC50=10nM).InhibitsHIV-1replicationinvitro.AlsopotentlyinhibitsMKK1(MEK1)(IC50=0.5nM)andprovidesneuroprotectionbybindingtokainatereceptors.

CompoundLibraries

ArctigeninisalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxI.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt372.42
FormulaC21H24O6
StorageDesiccateat-20°C
Purity≥98%(HPLC)
CASNumber7770-78-7
PubChemID64981
InChIKeyNQWVSMVXKMHKTF-JKSUJKDBSA-N
SmilesOC(C=C3)=C(OC)C=C3C[C@@H](C(OC2)=O)[C@H]2CC1=CC(OC)=C(OC)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO37.24100
ethanol9.3125mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight372.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.69mL13.43mL26.85mL
5mM0.54mL2.69mL5.37mL
10mM0.27mL1.34mL2.69mL
50mM0.05mL0.27mL0.54mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet