Cdc20inhibitor;inhibitsCdc20-substrateinteraction.Blockssubstrate-mediatedCdc20loADIngontotheanaphase-promotingcomplex(APC).InhibitsAPC-dependentubiquitylation.ProlongsmitoticdurationinRPE1cellsincombinationwithproTAME(prodrugofTAME(Cat.No.4506))invitro.
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Thefollowingdataisbasedontheproductmolecularweight438.65.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.