Proteinsynthesisinhibitor(blockstranslation).Potentactivatorofstress-activatedproteinkinases(JNK/SAPK)andp38MAPkinase.ActsasapotentsignalingagoNISTtoselectivelyelicithomologousdesensitizationofimmediateearlygeneinduction(c-fos,fosB,c-jun,junBandjunD).
M.Wt | 265.31 |
Formula | C14H19NO4 |
Storage | Desiccateat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 22862-76-6 |
PubChemID | 253602 |
InChIKey | YKJYKKNCCRKFSL-RDBSUJKOSA-N |
Smiles | O[C@H]1CN[C@H](CC2=CC=C(OC)C=C2)[C@@H]1OC(C)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 26.53 | 100 | |
ethanol | 13.27 | 50 |
Thefollowingdataisbasedontheproductmolecularweight265.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.77mL | 18.85mL | 37.69mL |
5mM | 0.75mL | 3.77mL | 7.54mL |
10mM | 0.38mL | 1.88mL | 3.77mL |
50mM | 0.08mL | 0.38mL | 0.75mL |