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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Ani 9/6076/50/50 mg
产品编号:6076/50
市  场 价:¥13900.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$695.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Ani 9/6076/50/50 mg
商品介绍
Description:PotentandselectiveTMEM16A(Anoctamin-1;ANO1)blocker
ChemicalName:2-(4-Chloro-2-methylphenoxy)-N'-(2-methoxybenzylidene)acetohydrazide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveTMEM16A(Anoctamin-1;ANO1)blocker(IC50=77nM).DisplaysnoeffectonANO2activity(at10μM).AlsoexhibitsnoeffectonintracellularcalciumsignalingorCFTRandENaCchannelactivity(at30μM).

TechnicalData

M.Wt332.78
FormulaC17H17ClN2O3
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber356102-14-2
PubChemID9556542
InChIKeyKDALDZRKOBJXIE-VXLYETTFSA-N
SmilesCOC1=C(C=CC=C1)/C=N/NC(COC2=C(C=C(C=C2)Cl)C)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO33.28100
ethanol3.3310mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight332.78.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3mL15.02mL30.05mL
5mM0.6mL3mL6.01mL
10mM0.3mL1.5mL3mL
50mM0.06mL0.3mL0.6mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet