InhibitorofNF-κBsignaling;alsoattenuatesconcanavaline-inducedIFNγproductioninmurineTcells(IC50=1.7μM).Blocksandrogenreceptor(AR)expressioninAR-expressingC4-2cells.ActivatesNrf2inBEAS-2Bcellsinresponsetocigarettesmokeextract.
| M.Wt | 350.45 |
| Formula | C20H30O5 |
| Storage | Storeat-20°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 5508-58-7 |
| PubChemID | 452937 |
| InChIKey | BOJKULTULYSRAS-UQZPWQSVSA-N |
| Smiles | C=C1CC[C@@]([C@@](CO)(C)[C@H](O)CC3)([H])[C@]3(C)[C@@H]1C/C=C2[C@H](O)COC/2=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 35.05 | 100 | |
| ethanol | 3.5 | 10 |
Thefollowingdataisbasedontheproductmolecularweight350.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.85mL | 14.27mL | 28.53mL |
| 5mM | 0.57mL | 2.85mL | 5.71mL |
| 10mM | 0.29mL | 1.43mL | 2.85mL |
| 50mM | 0.06mL | 0.29mL | 0.57mL |



