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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Anastrozole/3388/50/50 mg
产品编号:3388/50
市  场 价:¥15300.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$765.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Anastrozole/3388/50/50 mg
商品介绍
Description:Potentaromatase(CYP19)inhibitor
AlternativeNames:ZD1033
ChemicalName:α1,α1,α3,α3-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandhighlyselectivearomatase(CYP19)inhibitor(IC50=15nM)thathasnodiscernIBLeeffectonadrenocorticoidhormonesynthesis.Reducesplasmaestrogenlevelsandexhibitsantitumoractivityinvivo.Orallyactive.

LicensingInformation

SoldforresearchpurposesonlyunderagreementfromAstraZeneca

CompoundLibraries

AnastrozoleisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt293.37
FormulaC17H19N5
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber120511-73-1
PubChemID2187
InChIKeyYBBLVLTVTVSKRW-UHFFFAOYSA-N
SmilesCC(C)(C#N)C1=CC(CN2C=NC=N2)=CC(C(C)(C)C#N)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO29.34100
ethanol29.34100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight293.37.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.41mL17.04mL34.09mL
5mM0.68mL3.41mL6.82mL
10mM0.34mL1.7mL3.41mL
50mM0.07mL0.34mL0.68mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet