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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Amlodipine besylate/2571/50/50 mg
产品编号:2571/50
市  场 价:¥1900.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$95.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Amlodipine besylate/2571/50/50 mg
商品介绍
Description:Ca2+channelblocker(L-type)
AlternativeNames:Norvasc
ChemicalName:2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylicacid3-ethyl5-methylesterbenzenesulfonate
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

L-typecalciumchannelblockerthatdisplaysantihypertensiveproperties.InhibitsCa2+-inducedcontractionsindepolarizedrataorta(IC50=1.9nM)anddisplaysvasoprotectiveeffectsincardiovasculardisease.InhibitsproliferationofhumanvascularsmoothmusclecellsandepidermoidcarcinomaA431cells(IC50=25μM).

CompoundLibraries

AmlodipinebesylateisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt567.05
FormulaC20H25ClN2O5.C6H6O3S
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber111470-99-6
PubChemID60496
InChIKeyZPBWCRDSRKPIDG-UHFFFAOYSA-N
SmilesOS(=O)(=O)C1=CC=CC=C1.CCOC(=O)C1=C(COCCN)NC(C)=C(C1C1=CC=CC=C1Cl)C(=O)OC

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO56.7100
ethanol28.3550
water5.6710

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight567.05.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.76mL8.82mL17.64mL
5mM0.35mL1.76mL3.53mL
10mM0.18mL0.88mL1.76mL
50mM0.04mL0.18mL0.35mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet