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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/TC AC 28/6105/1/1 mg
产品编号:6105
市  场 价:¥1780.00
场      地:美国(厂家直采)
产品分类: 蛋白类>多肽>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$89.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/TC AC 28/6105/1/1 mg
商品介绍
Description:HighaffinityBETbromodomainligand
ChemicalName:6-(1H-Indol-4-yl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-aceticacidmethylester
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighaffinityBETbromodomainligand(Kdvaluesare40and800nMforBrd2(2)andBrd2(1),respectively).Exhibits20-foldselectivelyforthesecondoverthefirstbromodomain.

LicensingInformation

SoldunderlicencefromtheUniversityofDundee.

TechnicalData

M.Wt415.44
FormulaC23H21N5O3
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber1809296-92-1
PubChemID118121364
InChIKeyRARZHTSXOQRRPR-UHFFFAOYNA-N
SmilesCOC(CC1N=C(C2=CC(OC)=CC=C2N3C(C)=NN=C13)C4=C5C=CNC5=CC=C4)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO2.085mMwithgentlewarming
ethanol2.085mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight415.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.41mL12.04mL24.07mL
5mM0.48mL2.41mL4.81mL
10mM0.24mL1.2mL2.41mL
50mM0.05mL0.24mL0.48mL