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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/B I09/6009/10/10 mg
产品编号:6009
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/B I09/6009/10/10 mg
商品介绍
Description:IRE1endonucleaseinhibitor;cellpermeable
ChemicalName:7-(1,3-Dioxan-2-yl)-1,2,3,4-tetrahydro-8-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

IRE-1RNaseinhibitor(IC50=1.23μM).InhibitsIRE-1/XBP1pathway.Cellpermeable.Inhibitsgrowthofhumanchroniclymphocyticleukemia(CLL)cellsinvitroandpromotesCLLregressioninamousemodel.

TechnicalData

M.Wt303.31
FormulaC16H17NO5
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber1607803-67-7
PubChemID86290458
InChIKeyUYYMWNUDIOPESF-UHFFFAOYSA-N
SmilesOC1=CC=C2C3=C(C(OC2=C1C4OCCCO4)=O)CNCC3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO15.1750

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight303.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.3mL16.48mL32.97mL
5mM0.66mL3.3mL6.59mL
10mM0.33mL1.65mL3.3mL
50mM0.07mL0.33mL0.66mL