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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/TAT-Gap19/6227/1/1 mg
产品编号:6227
市  场 价:¥4500.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$225.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/TAT-Gap19/6227/1/1 mg
商品介绍
Description:Cx43hemichannelblocker
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Cx43hemichannelblocker(IC50~7μM).NosignificantaffinityforgapjunctionsorPanx1channels.N-terminaltransactivatoroftranscription(TAT)motifpromotesmembranepermeABIlityandincreasesinhibitoryeffectofGap19(Cat.No.5353).Activeinvivo.Brainpenetrant.

TechnicalData

M.Wt2703.28
FormulaC119H212N46O26
SequenceYGRKKRRQRRRKQIEIKKFK
StorageStoreat-20°C
CASNumber1507930-54-2
PubChemID127021051
InChIKeyALNCFPIRTLVJPY-XELKYWHDNA-N
Smiles[H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto1mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight2703.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.37mL1.85mL3.7mL
5mM0.07mL0.37mL0.74mL
10mM0.04mL0.18mL0.37mL
50mM0.01mL0.04mL0.07mL