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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/25-Hydroxycholesterol/5741/10/10 mg
产品编号:5741
市  场 价:¥1780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$89.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/25-Hydroxycholesterol/5741/10/10 mg
商品介绍
Description:Antiviral;alsoα-crystallin(cryAB)chaperone
ChemicalName:Cholest-5-ene-3β,25-diol
Purity:≥95%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Antiviral.StimulatesexpressionofmiR-185microRNAwhichinhibitsthehepatitisCviruslifecycleviainhibitionofcholesterolbiosynthesisandviruscellmembranefusion.Alsoα-crystallin(cryAB)chaperone(Kd=10.1μM).Blocksα-crystallinaggregationandpartiallyreversescataractformationbybindingandstABIlizingsolubleformsofcryABinvitroandinvivo.

TechnicalData

M.Wt402.65
FormulaC27H46O2
StorageStoreat-20°C
Purity≥95%(HPLC)
CASNumber2140-46-7
PubChemID65094
InChIKeyINBGSXNNRGWLJU-ZHHJOTBYSA-N
SmilesO[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCCC(C)(O)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO4.0310mMwithgentlewarming
ethanol20.1350

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight402.65.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.48mL12.42mL24.84mL
5mM0.5mL2.48mL4.97mL
10mM0.25mL1.24mL2.48mL
50mM0.05mL0.25mL0.5mL