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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/(S)-Equol/6158/10/10 mg
产品编号:6158
市  场 价:¥2380.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$119.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/(S)-Equol/6158/10/10 mg
商品介绍
Description:Potentestrogenreceptorβ(ERβ)agoNIST;dihydrotestosteroneantagonist
ChemicalName:(3S)-3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentestrogenreceptorβ(ERβ)agonist(EC50=65nM).Exhibits13-foldselectivityforERβoverERα.Atheroprotective.Protectsagainstt-BHPinducedapoptosisandattenuatesERstressinHUVECs.ActivatesNrf2signalinginvitroandinvivo.Inhibitstumorgrowth.Alsodihydrotestosteroneantagonistinvivo.

TechnicalData

M.Wt242.27
FormulaC15H14O3
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber531-95-3
PubChemID91469
InChIKeyADFCQWZHKCXPAJ-GFCCVEGCSA-N
SmilesOC1=CC=C([C@H]2COC3=CC(O)=CC=C3C2)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO24.23100
ethanol24.23100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight242.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.13mL20.64mL41.28mL
5mM0.83mL4.13mL8.26mL
10mM0.41mL2.06mL4.13mL
50mM0.08mL0.41mL0.83mL