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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/7α,25-Dihydroxycholesterol/6277/10/10 mg
产品编号:6277
市  场 价:¥6780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$339.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/7α,25-Dihydroxycholesterol/6277/10/10 mg
商品介绍
Description:HighlypotentGPR183(EBI2)agoNIST
ChemicalName:(3β,7α)-Cholest-5-ene-3,7,25-triol
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighlypotentGPR183(EBI2)agonist(EC50=140pM)andputativenaturalligandforGPR183.RegulatesmigrationofBandTcellsexpressingGPR183invivo.DesensitizesBcellsandreducestheirmovementtosplenicfollicles.

TechnicalData

M.Wt418.65
FormulaC27H46O3
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber64907-22-8
PubChemID11954197
InChIKeyBQMSKLCEWBSPPY-IKVTXIKFSA-N
SmilesO[C@H](C1)CC[C@@]2(C)C1=C[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCCC(C)(O)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO4.1910mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight418.65.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.39mL11.94mL23.89mL
5mM0.48mL2.39mL4.78mL
10mM0.24mL1.19mL2.39mL
50mM0.05mL0.24mL0.48mL