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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Lys-CoA/5103/1/1 mg
产品编号:5103
市  场 价:¥6380.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$319.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Lys-CoA/5103/1/1 mg
商品介绍
Description:Selectivep300inhibitor
ChemicalName:S-[2-[[(5S)-5-(Acetylamino)-6-amino-6-oxohexyl]amino]-2-oxoethyl]coenzymeAtrifluoroacetate
Purity:≥95%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivep300histoneacetyltransferase(HAT)inhibitor(IC50=50-500nM).Exhibitsapproximately100-foldselectivityforp300overPCAF(IC50=200μM).Inhibitsp300-dependenttranscription.Activeinvivo.

TechnicalData

M.Wt1108.82
FormulaC31H53N10O19P3S.C2HF3O2
StorageStoreat-20°C
Purity≥95%(HPLC)
SmilesO[C@H]([C@@H]1OP(O)(O)=O)[C@@H](O[C@@H]1COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSCC(NCCCC[C@@H](C(N)=O)NC(C)=O)=O)=O)=O)(O)=O)(O)=O)N2C3=NC=NC(N)=C3N=C2.OC(C(F)(F)F)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
water6.996.3

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight1108.82.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.9mL4.51mL9.02mL
5mM0.18mL0.9mL1.8mL
10mM0.09mL0.45mL0.9mL
50mM0.02mL0.09mL0.18mL