请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Tubastatin A hydrochloride/6270/10/10 mg
产品编号:6270
市  场 价:¥2380.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$119.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Tubastatin A hydrochloride/6270/10/10 mg
商品介绍
Description:PotentHDAC6inhibitor
ChemicalName:N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamidehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentHDAC6inhibitor(IC50=0.015μM).ExhibitssomeselectivelyforHDAC6overHDAC8and1(IC50valuesare0.854and16.4μM,respectively).Induceselevatedlevelsofα-tubulinandprotectsagainstglutathione-inducedoxidativestressinprimaryneuronalcellculture.

TechnicalData

M.Wt371.86
FormulaC20H21N3O2.HCl
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber1310693-92-5
PubChemID57336514
InChIKeyLJTSJTWIMOGKRJ-UHFFFAOYSA-N
SmilesCN1CCC2=C(C3=CC=CC=C3N2CC4=CC=C(C(NO)=O)C=C4)C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO3.7210mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight371.86.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.69mL13.45mL26.89mL
5mM0.54mL2.69mL5.38mL
10mM0.27mL1.34mL2.69mL
50mM0.05mL0.27mL0.54mL