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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AC 265347/6165/10/10 mg
产品编号:6165
市  场 价:¥2980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$149.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AC 265347/6165/10/10 mg
商品介绍
Description:CaSRbiasedallostericmodulator
ChemicalName:α-(2,4-Dimethylphenyl)-α-methyl-2-benzothiazolemethanol
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

CaSRbiasedallostericmodulator(pEC50=7.8-8.1).Calcimimetic.DisplaysABIlitytobiassignallingtowardstheaccumulationofPERK1/2andIP1.Reducesparathyroidhormone(PTH)levelsinratserumwithoutinducingthereleaseofcalcitonin.ExhibitsnosignificantactivationofhumanGABABortypeIPTHreceptors.Orallyactive.

TechnicalData

M.Wt283.39
FormulaC17H17NOS
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber1253901-26-6
PubChemID52943938
InChIKeyIGSZVEPQZANNAB-UHFFFAOYSA-N
SmilesCC1=CC(C)=C(C(O)(C2=NC3=CC=CC=C3S2)C)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO28.34100
ethanol28.34100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight283.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.53mL17.64mL35.29mL
5mM0.71mL3.53mL7.06mL
10mM0.35mL1.76mL3.53mL
50mM0.07mL0.35mL0.71mL