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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/PSB 12379/6083/10/10 mg
产品编号:6083
市  场 价:¥5300.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$265.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/PSB 12379/6083/10/10 mg
商品介绍
Description:Ecto-5"-nucleotidase(CD73)inhibitor
ChemicalName:N6-Benzyl-α,β-methyleneadenosine5'-diphosphatedisodiumsalt
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectivehighaffinityEcto-5'-nucleotidase/CD73inhibitor(Kivaluesare2.21and9.03nMathumanandratCD73,respectively).Blocksecto-5'-nucleotidase-mediatedadenosineproductionbypreventingtheconversionofAMPtoadenosine.Exhibitsselectivityoverotherecto-nucleotidasesandADP-activatedP2Yreceptorstested.

TechnicalData

M.Wt559.31
FormulaC18H21N5Na2O9P2
StorageStoreat-20°C
Purity≥98%(HPLC)
SmilesO[C@H]1[C@@H](O)[C@H](N2C3=NC=NC(NCC4=CC=CC=C4)=C3N=C2)O[C@@H]1COP(CP(O)(O[Na])=O)(O[Na])=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleinwater(suppliedpre-dissolvedataconcentrationof10mM)

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight559.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.79mL8.94mL17.88mL
5mM0.36mL1.79mL3.58mL
10mM0.18mL0.89mL1.79mL
50mM0.04mL0.18mL0.36mL