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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/DG 041/6240/10/10 mg
产品编号:6240
市  场 价:¥3580.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$179.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/DG 041/6240/10/10 mg
商品介绍
Description:PotentandselectiveEP3antagoNIST;antiplateletandantithrombotic
ChemicalName:(2E)-3-[1-[(2,4-Dichlorophenyl)methyl]-5-fluoro-3-methyl-1H-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveEP3antagonist(IC50=4.6nM).InhibitsPGE2facilitationofplateletaggregationinvitroandexvivo.DisplaysgoodplasmaandmetabolicstABIlity.Doesnotaffectbleedingtimeinrats.Antiplateletandantithrombotic.

TechnicalData

M.Wt592.32
FormulaC23H15Cl4FN2O3S2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber861238-35-9
PubChemID11296282
InChIKeyBFBTVZNKWXWKNZ-HWKANZROSA-N
SmilesCC1=CN(C2=C(C=C(C=C12)F)/C=C/C(NS(=O)(C3=CC(Cl)=C(S3)Cl)=O)=O)CC4=C(C=C(C=C4)Cl)Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO59.23100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight592.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.69mL8.44mL16.88mL
5mM0.34mL1.69mL3.38mL
10mM0.17mL0.84mL1.69mL
50mM0.03mL0.17mL0.34mL