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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/QAQ dichloride/5470/10/10 mg
产品编号:5470
市  场 价:¥3700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$185.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/QAQ dichloride/5470/10/10 mg
商品介绍
Description:PhotoswitchableNav,KvandCavchannelblocker
ChemicalName:2,2'-[1,2-Diazenediylbis(4,1-phenyleneimino)bis[N,N,N-triethyl-2-oxo-ethanaminium]dichloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PhotoswitchableNav,CavandKvchannelblocker.Blockschannelsinthetransconformation.Switchesconformationfromcistotransat500nmandtranstocisat380nm.Normallymembraneimpermeant,butentersnociceptiveneuronsviaionchannelsactivatedbynoxiousstimuli,particularlyTRPV1.ExhibitsopticallyreversIBLelocalanesthesiainrats.

TechnicalData

M.Wt567.59
FormulaC28H44Cl2N6O2
StorageStoreat-20°C
Purity≥98%(HPLC)
PubChemID91826091
InChIKeyVHURBRSYOFCHNY-UHFFFAOYSA-N
SmilesO=C(C[N+](CC)(CC)CC)NC(C=C2)=CC=C2/N=N/C1=CC=C(NC(C[N+](CC)(CC)CC)=O)C=C1.[Cl-].[Cl-]

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO5.6810
water28.3850

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight567.59.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.76mL8.81mL17.62mL
5mM0.35mL1.76mL3.52mL
10mM0.18mL0.88mL1.76mL
50mM0.04mL0.18mL0.35mL