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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Salvinorin B/5611/1/1 mg
产品编号:5611
市  场 价:¥1580.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$79.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Salvinorin B/5611/1/1 mg
商品介绍
Description:Activatestheκ-opioidDREADD(KORD)
ChemicalName:(2S,4aR,6aR,7R,9S,10aS,10bR)-2-(3-Furanyl)dodecahydro-9-hydroxy-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylicacidmethylester
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectiveκ-opioidDREADD(KORD)activator(EC50=11.8nM).SelectiveforKORDoverendogenousκopioidreceptorandarangeofotherrelatedtargets.Exhibitsnoanalgesicorataxiceffectsinwildtypemice.Inducesneuronalhyperpolarization,andmodifieslocomotoractivityandfeedingbehaviorinKORD-expressingmousemodels.Brainpenetrant.MetaboliteofsalvinorinA(Cat.No.2134).

TechnicalData

M.Wt390.43
FormulaC21H26O7
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber92545-30-7
PubChemID11440685
InChIKeyBLTMVAIOAAGYAR-CEFSSPBYSA-N
SmilesO=C3[C@]2([H])CC[C@@]([C@]([H])1[C@](C)2C[C@@H]([C@]4=COC=C4)O3)(C)[C@H]([C@@](OC)=O)C[C@H](O)C1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO7.8120

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight390.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.56mL12.81mL25.61mL
5mM0.51mL2.56mL5.12mL
10mM0.26mL1.28mL2.56mL
50mM0.05mL0.26mL0.51mL