EstrogenreceptorantagoNIST.Tamoxifen(Cat.No.0999)metabolite;exhibitsgreaterpotencythantheparentcompound.Chemotherapeuticagent.Alsoactivatesintein-linkedinactiveCas9,reducingoff-targetCRISPR-mediatedgeneediting;systemhas~25-foldhigherspecificitythanwtCas9.
M.Wt | 387.51 |
Formula | C26H29NO2 |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 68047-06-3 |
PubChemID | 449459 |
InChIKey | TXUZVZSFRXZGTL-QPLCGJKRSA-N |
Smiles | CCC(C3=CC=CC=C3)=C(C2=CC=C(OCCN(C)C)C=C2)/C1=CC=C(O)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 38.75 | 100 | |
ethanol | 19.38 | 50 |
Thefollowingdataisbasedontheproductmolecularweight387.51.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.58mL | 12.9mL | 25.81mL |
5mM | 0.52mL | 2.58mL | 5.16mL |
10mM | 0.26mL | 1.29mL | 2.58mL |
50mM | 0.05mL | 0.26mL | 0.52mL |
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.