请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Azidothymidine/4150/50/50 mg
产品编号:4150
市  场 价:¥1180.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$59.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Azidothymidine/4150/50/50 mg
商品介绍
Description:Selectivereversetranscriptaseinhibitor;antiretroviral
ChemicalName:3'-Azido-3'-deoxythymidine
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivereversetranscriptaseinhibitor.Exhibits100-foldselectivityforHIVreversetranscriptaseoverDNApolymeraseα.SuppressesHIV-1replicationandenhancescellviABIlityinHIV-1infectedTcells.Attenuatesgrowthofmultiplemyeloma(MM)cellsinvitroandreducesgrowthofMMtumorxenograftsinmice.Orallybioavailableandbrainpenetrant.Antiretroviralagent.AlsodecreasesCRISPR-mediatedhomologydirectedrepair(HDR)efficiency.

LicensingInformation

SoldforresearchpurposesunderagreementfromViiv.

TechnicalData

M.Wt267.24
FormulaC10H13N5O4
StorageStoreat-20°C
Purity≥99%(HPLC)
CASNumber30516-87-1
PubChemID35370
InChIKeyHBOMLICNUCNMMY-XLPZGREQSA-N
SmilesO=C1N([C@@H]2O[C@H](CO)[C@@H](N=[N+]=[N-])C2)C=C(C)C(N1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO26.72100
water13.3650

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight267.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.74mL18.71mL37.42mL
5mM0.75mL3.74mL7.48mL
10mM0.37mL1.87mL3.74mL
50mM0.07mL0.37mL0.75mL