NMDAreceptormodulator.MetaboliteofKetaminehydrochloride(Cat.No.3131).DecreasesintracellularD-serineconcentration(IC50=91nM)andaltersserineracemaseexpressioninPC-12cells.Exhibitsanalgesiceffectsinratpainmodels.S-enantiomerandracematealsoavailable.
M.Wt | 260.16 |
Formula | C12H14ClNO.HCl |
Storage | DesiccateatRT |
Purity | ≥98%(HPLC) |
CASNumber | 83777-68-8 |
PubChemID | 71743680 |
InChIKey | CLPOJGPBUGCUKT-UTONKHPSSA-N |
Smiles | ClC1=C([C@@]2(N)C(CCCC2)=O)C=CC=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 26.02 | 100 | |
water | 26.02 | 100 |
Thefollowingdataisbasedontheproductmolecularweight260.16.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.84mL | 19.22mL | 38.44mL |
5mM | 0.77mL | 3.84mL | 7.69mL |
10mM | 0.38mL | 1.92mL | 3.84mL |
50mM | 0.08mL | 0.38mL | 0.77mL |
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.