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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Amisulpride/2132/50/50 mg
产品编号:2132/50
市  场 价:¥2300.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$115.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Amisulpride/2132/50/50 mg
商品介绍
Description:SelectiveD2/D3receptorantagoNIST;atypicalantipsychoticagent
AlternativeNames:DAN2163
ChemicalName:4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-benzamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selectivedopamineD2andD3receptorantagonist.Kivaluesare2.8and3.2nMrespectivelyforhumanD2andD3and>1000nMforhumanD1,D4andD5receptors.ShowsselectivityforpresynapticdopamineautoreceptorsatlowdosesandblockspostsynapticD2/D3receptorsathigherdoses.PreferentiallyinteractswithlimbicD2-likereceptorsinvivo.Atypicalantipsychotic/antischizophrenicagentwithlimitedextrapyrimidalsideeffectsandaprofiledistinctfromthatofhaloperidolandremoxipride.

TechnicalData

M.Wt369.48
FormulaC17H27N3O4S
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber71675-85-9
PubChemID2159
InChIKeyNTJOBXMMWNYJFB-UHFFFAOYSA-N
SmilesCCN1CCCC1CNC(=O)C1=C(OC)C=C(N)C(=C1)S(=O)(=O)CC

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
1eq.HCl9.2425mMwithgentlewarming
DMSO18.4750

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight369.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.71mL13.53mL27.07mL
5mM0.54mL2.71mL5.41mL
10mM0.27mL1.35mL2.71mL
50mM0.05mL0.27mL0.54mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet