Na+channelblocker.DefinestheI2A-amiloridesensitiveandI2B-amilorideinsensitiveimidazolinebindingBlocksTRPP3,acidsensing-(ASIC)andmechanogatedmembrane-ionchannels,aswellastheNa+/H+exchanger.Alsoinhibitsurokinase-typeplasminogenactivator(uPA);hasnoeffectontissue-typeplasminogenactivator.
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Thefollowingdataisbasedontheproductmolecularweight266.09.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.