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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/α-Amanitin/4025/1/1 mg
产品编号:4025/1
市  场 价:¥4980.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$249.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/α-Amanitin/4025/1/1 mg
商品介绍
Description:InhibitorofRNApolymeraseII
ChemicalName:cyclo[L-Asparaginyl-4-hydroxy-L-proly-(R-4,5-dihydroxy-L-isoleucyl-6-hydroxy-2-mercapto-L-tryptophylglycyl-L-isoleucylglycyl-L-cysteinyl]cyclic(4→8)-sulfide(R)-S-oxide
Purity:≥95%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofRNApolymeraseII.Inhibitstranscriptionineukaryoticcells.BindsandblocksthelargestsubunitsofRNApolymeraseII,preventingnewribonucleotidesfromincorporatingintothenascentRNAchain.Potentamatoxin.

TechnicalData

M.Wt918.97
FormulaC39H54N10O14S
StorageStoreat-20°C
Purity≥95%(HPLC)
CASNumber23109-05-9
PubChemID441541
InChIKeyCIORWBWIBBPXCG-JAXJKTSHSA-N
SmilesO=[C@@](N[C@@](C(N[C@@H](CC2=C(S4=O)NC3=C2C=CC(O)=C3)C(NCC(N[C@]([H])5[C@@H](C)CC)=O)=O)=O)([H])[C@@H](C)[C@@H](O)CO)[C@@H]1C[C@@H](O)CN1C([C@H](CC(N)=O)NC([C@H](C4)NC(CNC5=O)=O)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
ethanol4.595
water4.595

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight918.97.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.09mL5.44mL10.88mL
5mM0.22mL1.09mL2.18mL
10mM0.11mL0.54mL1.09mL
50mM0.02mL0.11mL0.22mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet