Potentandselective5-HT2Areceptorantagonist(Kivaluesare0.13,4.55,40,62and1570nMat5-HT2A,α1,5-HT2C,D2and5-HT1Arespectively).Centrallyactivefollowingsystemicadministrationinvivo.
AltanserinhydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 447.95 |
| Formula | C22H22FN3O2S.HCl |
| Storage | Desiccateat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 1135280-78-2 |
| PubChemID | 24978536 |
| InChIKey | JFPPLMAMMZZOEA-UHFFFAOYSA-N |
| Smiles | Cl.FC1=CC=C(C=C1)C(=O)C1CCN(CCN2C(=S)NC3=CC=CC=C3C2=O)CC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 8.96 | 20mMwithgentlewarming |
Thefollowingdataisbasedontheproductmolecularweight447.95.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.23mL | 11.16mL | 22.32mL |
| 5mM | 0.45mL | 2.23mL | 4.46mL |
| 10mM | 0.22mL | 1.12mL | 2.23mL |
| 50mM | 0.04mL | 0.22mL | 0.45mL |



