Sesquiterpenelactone.Inducesactivin/SMAD3signalinganddisruptsCripto-1/activinreceptortypeIIAinteraction.DisplaysantiproliferativeactivityinhumancolonadenocarcinomaHCT-8cells.
AlantolactoneisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 232.32 |
Formula | C15H20O2 |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 546-43-0 |
PubChemID | 72724 |
InChIKey | PXOYOCNNSUAQNS-AGNJHWRGSA-N |
Smiles | O=C3C([C@@]2([H])C=C1[C@@H](C)CCC[C@@](C)1C[C@]([H])2O3)=C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 23.23 | 100 | |
ethanol | 23.23 | 100 |
Thefollowingdataisbasedontheproductmolecularweight232.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 4.3mL | 21.52mL | 43.04mL |
5mM | 0.86mL | 4.3mL | 8.61mL |
10mM | 0.43mL | 2.15mL | 4.3mL |
50mM | 0.09mL | 0.43mL | 0.86mL |