请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Adenosine 5'-(α,β-methylene)diphosphate sodium salt/3633/10/10 mg
产品编号:3633/10
市  场 价:¥3900.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$195.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Adenosine 5'-(α,β-methylene)diphosphate sodium salt/3633/10/10 mg
商品介绍
Description:Ecto-5'-nucleotidase(CD73)inhibitor
AlternativeNames:AMPCP,APCP
ChemicalName:α,β-Methyleneadenosine5'-diphosphatemonosodiumsalt
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Ecto-5'-nucleotidase/CD73inhibitor.Blocksecto-5'-nucleotidase-mediatedadenosineproductionbypreventingtheconversionofAMPtoadenosine.Reversesthedoxorubicin-resistanceinecto-5'-nucleotidase-positiveMDRcells(MCF7/A6andL1210/A).Alsoincreasesrhodamineuptakeandinhibitsrhodamineeffluxfromecto-5'-nucleotidase-positiveMDRcells.Vasoconstrictor.

TechnicalData

M.Wt447.21
FormulaC11H16N5NaO9P2
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber89016-30-8
PubChemID91691113
InChIKeyRFGZKSPLJPHQMI-RDJRRFHDSA-M
SmilesNC1=C2C(N([C@@H]3O[C@H](COP(CP(O)(O[Na])=O)(O)=O)[C@@H](O)[C@@H]3O)C=N2)=NC=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleinwater(suppliedpre-dissolvedataconcentrationof10mM)

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight447.21.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.24mL11.18mL22.36mL
5mM0.45mL2.24mL4.47mL
10mM0.22mL1.12mL2.24mL
50mM0.04mL0.22mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet