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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Adapalene/2852/50/50 mg
产品编号:2852/50
市  场 价:¥7100.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$355.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Adapalene/2852/50/50 mg
商品介绍
Description:RARβandRARγagoNIST
AlternativeNames:CD271,Differin
ChemicalName:6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

RetinoicacidanalogthatisaRARβandRARγagonist(AC50valuesare2.2,9.3,22and>1000nMforRARβ,RARγ,RARαandRXRαreceptorsrespectively).Inhibitsproliferationandinducesapoptosisincolorectalcancercellinvitro.Displayscomedolyticactivity.

CompoundLibraries

AdapaleneisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt412.52
FormulaC28H28O3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber106685-40-9
PubChemID60164
InChIKeyLZCDAPDGXCYOEH-UHFFFAOYSA-N
SmilesCOC1=CC=C(C3=CC=C(C=C(C(O)=O)C=C4)C4=C3)C=C1C25CC(C6)CC(CC6C5)C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO10.3125

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight412.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.42mL12.12mL24.24mL
5mM0.48mL2.42mL4.85mL
10mM0.24mL1.21mL2.42mL
50mM0.05mL0.24mL0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet